Encapsulation of messenger RNA

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United States of America Patent

PATENT NO 9668980
SERIAL NO

14790562

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Abstract

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The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a mRNA solution and a lipid solution, wherein the mRNA solution and/or the lipid solution are at a pre-determined temperature greater than ambient temperature.

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Patent Owner(s)

Patent OwnerAddress
TRANSLATE BIO INC200 WEST STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DeRosa, Frank Lexington, US 261 2650
Heartlein, Michael Lexington, US 223 2893
Karve, Shrirang Lexington, US 119 337

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