Monocyte activation test better able to detect non-endotoxin pyrogenic contaminants in medical products

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United States of America Patent

PATENT NO 9671411
APP PUB NO 20150285819A1
SERIAL NO

14679651

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Abstract

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An improved monocyte activation test is described that is better able to detect non-endotoxin pyrogens in medical products, in which a sample is incubated with a monocyte-containing reagent in an assay system comprising at least one surface comprising polypropylene. The invention also concerns assay systems for use in these tests that include at least one microtiter well having at least one interior surface comprising polypropylene and having a shape such that monocyte-containing reagent is concentrated in the well to provide greater cell to cell contact. The invention also relates to a diagnostic kit that can be used to test for the presence of non-endotoxin pyrogens in a sample.

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Patent Owner(s)

Patent OwnerAddress
BAXTER INTERNATIONAL INCDEERFIELD IL 60015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Patel, Mehul Malvern, US 218 7464
Poole, Stephen London, GB 15 91

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