Nanoparticles for controlled lysis of blood clots

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United States of America Patent

PATENT NO 9675560
APP PUB NO 20150064267A1
SERIAL NO

14471616

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Abstract

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Fibrinolytic nanoparticles including a polymeric core having a surface that is functionalized with a cationic amphiphilic compound, and a fibrinolytic agent dispersed within the core, are described herein. The fibrinolytic nanoparticles can be used in method of dissolving a blood clot in a subject by administering to the subject a therapeutically effective amount of fibrinolytic nanoparticles.

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Patent Owner(s)

  • THE CLEVELAND CLINIC FOUNDATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ramamurthi, Anand Pepper Pike, US 6 15
Sivaraman, Balakrishnan Westlake, US 5 4
Sylvester, Andrew Richmond, US 3 2

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