Manufacturing method for 1,4-butanediol, microbe, and gene

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United States of America Patent

PATENT NO 9677096
SERIAL NO

14440116

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of manufacturing 1,4-butanediol through acetyl-CoA, acetoacetyl-CoA, 3-hydroxybutyryl-CoA, crotonyl-CoA, and 4-hydroxybutyryl-CoA by using a microbe and/or a culture thereof, wherein the microbe in the manufacturing method for 1,4-butanediol includes any one of genes among (a) a gene that has a base sequence of sequence number 1, (b) a gene that has a base sequence such that one or more bases are deleted, substituted, or added in a base sequence of sequence number 1, wherein the gene has a base sequence with an identity greater than or equal to 90% with respect to the base sequence of sequence number 1, and (c) a gene that hybridizes with a gene that has a base sequence complementary with a gene that has a base sequence described in sequence number 1 on a stringent condition, and includes any one or more genes among (d) genes that have base sequences of sequence numbers 2 to 9, (e) genes that have base sequences such that one or more bases are deleted, substituted, or added in base sequences of sequence numbers 2 to 9, wherein the genes have base sequences with an identity greater than or equal to 90% with respect to original base sequences thereof, and (f) genes that hybridize with genes that have base sequences complementary with genes that have base sequences of sequence numbers 2 to 9 on a stringent condition.

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Patent Owner(s)

  • SHOWA DENKO K.K.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoki, Hirobumi Tokyo, JP 27 83
Hashimoto, Yoko Tokyo, JP 20 276
Kokido, Yuzuru Tokyo, JP 11 0
Yoneda, Tadashi Tokyo, JP 43 169

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