Biological chip hybridization system

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United States of America Patent

PATENT NO 9677133
SERIAL NO

14006540

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Abstract

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A hybridization system is provided, which comprises a biological chip having a substrate (1) with a probe dot matrix (3) and a cover plate (2) with at least two through-holes (4), where a hybrid chamber (5) is formed between the substrate (1) and the cover plate (2), at least two fluid channels (6) are interconnected respectively with the hybrid chamber (5) by the two through-holes (4), and a fluid control device is interconnected with the fluid channels (6). The biological chip hybridization system integrates hybridizing, cleaning and drying functions, uses power provided by the fluid control device as the drive force for promoting the liquid flow for automatically reciprocation flow in the fluid channels (6) and the chamber (5) to achieve a dynamic hybridization, thus improving the hybrid efficiency and uniformity, and achieving automatic control.

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Patent Owner(s)

  • CAPITALBIO CORPORATION;TSINGHUA UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Duan, Liqing Beijing, CN 1 1
Gao, Huafang Beijing, CN 8 14
Song, Xiumei Beijing, CN 1 1
Wang, Dong Beijing, CN 547 3644
Wang, Guoqing Beijing, CN 67 218
Wang, Pinhong Beijing, CN 3 5
Xing, Wanli Beijing, CN 40 120
Ye, Jiaming Beijing, CN 19 61
Zhang, Jinxiu Beijing, CN 3 7
Zhao, Kaijun Beijing, CN 6 14

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