Pyrrolo[2,3-D]pyrimidine derivatives, process for their preparation and their use as kinase inhibitors

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United States of America Patent

PATENT NO 9682083
APP PUB NO 20160166575A1
SERIAL NO

14889987

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Abstract

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The present invention relates to 6-amino-7-deaza-purine derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions containing these compounds.

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NERVIANO MEDICAL SCIENCES S R L20014 NERVIANO (MI)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Angiolini, Mauro Gavirate, IT 13 58
Buffa, Laura Rossiglione, IT 4 28
Menichincheri, Maria Milan, IT 45 420
Motto, Ilaria Nerviano, IT 10 37
Polucci, Paolo Cassina Rizzardi, IT 21 147
Traquandi, Gabriella Milan, IT 38 814
Zuccotto, Fabio Milan, IT 16 169

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