Method for production of antibody

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United States of America Patent

PATENT NO 9683027
SERIAL NO

12734094

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Abstract

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The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.

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Patent Owner(s)

  • CHUGAI SEIYAKU KABUSHIKI KAISHA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kiyasu, Tatsuya Tokyo, JP 12 12
Kuzumaki, Akihiro Tokyo, JP 3 7
Tabata, Kazuyuki Tokyo, JP 5 7
Yamada, Yoshiki Tokyo, JP 65 644
Yamashiro, Mai Tokyo, JP 3 7

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