Optogenetic control of endothelial cells

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United States of America Patent

PATENT NO 9687672
SERIAL NO

14421744

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Abstract

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The invention features methods for regulating vascular properties by controlling the membrane properties of endothelial cells using optogenetics and light. The invention features methods to transport therapeutics across the vascular barrier into tissues such as the brain and the lung, with high spatial and temporal precision, and for controlling vascular properties such as vascular tone, arterial diameter, and vascular growth.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02140
BROWN UNIVERSITY69 BROWN STREET BOX 1822 PROVIDENCE RI 02912

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Tyler C Quincy, US 3 2
Moore, Christopher I Pawtucket, US 6 7

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