Selective EP4 receptor antagonistic substance for treatment of cancer

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United States of America Patent

PATENT NO 9688674
SERIAL NO

14547247

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Abstract

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This invention provides a medicament for the treatment of cancer, which cause a reduction of cancer. This invention relates to use of a compound which has inhibitory activities against prostaglandin E2 receptor (EP4 receptor) and is represented by the following general formula (I), (II), (III), or (IV), or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt for the manufacture of a medicament for the treatment of cancer. The invention relates to a method for treatment of cancer comprising administering the compound or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising the compound or the salt to humans or animals. The compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition may be used in combination with one or more second active agents.

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Patent Owner(s)

Patent OwnerAddress
ASKAT INC4-37-2 HIROJIHONMACHI SHOWA-KU NAGOYA 466-0841

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koizumi, Shinichi Aichi, JP 33 166
Nonomura, Kazuhiko Aichi, JP 15 140
Okumura, Takako Aichi, JP 18 34
Take, Yukinori Aichi, JP 8 18

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