Functional polymer film-coated particle having high drug content, tablet containing same, and methods for production thereof

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United States of America Patent

PATENT NO 9693965
APP PUB NO 20160120813A1
SERIAL NO

14889657

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Abstract

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Provided are functional drug-containing particles which can be compressed into tablets and in particular, to orally disintegrating tablets by employing any of a dry molding method, a wet molding method, or a humidifying drying method. The functional drug-containing particles comprise substantially spherical drug-containing particles essentially including drug and a binder, the functional drug-containing particles including a functional polymer film selected from the group consisting of an enteric film, a release control film, and a bitter taste masking film, an average particle diameter of said functional drug-containing particles being 400 μm or less, a particle diameter ratio D90/D10 of the functional drug-containing particles with respect to particle size distribution calculated on a volumetric basis being 1.65 or more, or a coefficient of variation in particle diameters being 24% or more.

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Patent Owner(s)

Patent OwnerAddress
POWREX CORPORATION121-1 KITA-ITAMI 8-CHOME ITAMI-SHI HYOGO 6640831
ZENSEI PHARMACEUTICAL INDUSTRIES CO LTDOSAKA 5938307

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hayashida, Tomohiro Osaka, JP 9 139
Hizaki, Masaya Osaka, JP 7 5
Kinoshita, Naotoshi Hyogo, JP 10 60
Nakano, Yoshio Osaka, JP 47 790
Yamazaki, Junji Osaka, JP 5 15

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