Use of rhodamine dyes to reduce alveolar surface tension

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United States of America Patent

PATENT NO 9693990
SERIAL NO

14940675

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Abstract

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Rhodamine dye is delivered to regions of a lung having heterogeneous alveolar flooding by alveolar liquid, thereby lowering the surface tension of the alveolar liquid so as to lessen ventilation injury directly and, by promoting equitable redistribution of the alveolar liquid among the alveoli of the lung, indirectly. The rhodamine dye is delivered with an albumin and/or an exogenous surfactant. Exemplary rhodamine dyes include sulforhodamine B and rhodamine WT.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYSTEVENS INSTITUTE OF TECHNOLOGY CASTLE POINT ON HUDSON HOBOKEN NJ 07030

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Perlman, Carrie E New York, US 6 7

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