Compounds for the treatment and prevention of infections
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United States of America Patent
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Jul 4, 2017
Grant Date -
Jun 18, 2015
app pub date -
Jul 15, 2013
filing date -
Jul 16, 2012
priority date (Note) -
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Abstract
Provided herein are compounds of Formula (I) or (II): (I) (II) pharmaceutically acceptable salts, tautomers, prodrugs, and stereoisomers thereof, and pharmaceutical compositions thereof, wherein X, RN, R1, R3, R4, p, and m are as defined herein. Such compounds and compositions have been found useful in the treatment or prevention of viral infections, e.g., polyomaviral infections, and are further envisioned useful in treatment or prevention of other pathogenic conditions associated with endosomal trafficking. Methods of treating or preventing an infection by a pathogen secreting an AB5 toxin is also contemplated.
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