PDGF and VEGF aptamers having improved stability and their use in treating PDGF and VEGF mediated diseases and disorders

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9695424
SERIAL NO

14909305

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Abstract

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Aptamers having improved stability against nucleases that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF aptamer and a VEGF aptamer are provided. Pharmaceutical compositions comprising the aptamers and aptamer constructs are provided, as well as methods of treating conditions using the aptamers and aptamer constructs.

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Patent Owner(s)

Patent OwnerAddress
SOMALOGIC OPERATING CO INC2945 WILDERNESS LANE BOULDER CO 80301

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drolet, Daniel W Boulder, US 10 34
Gelinas, Amy D Lafayette, US 8 34
Janjic, Nebojsa Boulder, US 100 2000
Vrkljan, Michael Mead, US 3 9
Zhang, Chi Superior, US 419 2663

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