Formulations and methods for stabilizing PCR reagents

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United States of America Patent

PATENT NO 9725703
SERIAL NO

14654457

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Abstract

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Described herein are stabilized polymerase compositions comprising a polymerase and an polymerase stabilizing agent, such as a non-detergent zwitterionic stabilizer or a cationic ester disclosed, for use in nucleic acid amplification or nucleic acid sequencing. Compositions are provided for the stabilization of one or more polymerases in a single stabilized liquid formulation. Also disclosed are methods for making and using stabilized polymerase compositions and kits for nucleic acid amplification and sequencing comprising the stabilized polymerase compositions provided.

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Patent Owner(s)

  • BIOMATRICA, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Los Rios Stephanie San Diego, US 8 34
Ghirmai, Senait San Diego, US 2 44
Liberal, Vasco San Diego, US 4 16
Muller, Rolf San Diego, US 211 3747
Whitney, Scott E San Diego, US 23 368
Wilkinson, Steven P San Diego, US 10 74

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