Nucleic acid particles, methods and use thereof

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United States of America Patent

PATENT NO 9737557
SERIAL NO

14811263

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Abstract

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The present invention provides, among other things, a particle which includes a core comprised of self-assembled one or more nucleic acid molecules, the core being characterized by an ability to adopt at least two configurations: a first configuration having a first greatest dimension greater than 2 μm and; a second configuration having a second greatest dimension less than 500 nm, wherein addition of a film coating converts the core from its first configuration to its second configuration. Methods of making and using of provided particles are also disclosed.

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Patent Owner(s)

  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hammond, Paula T Newton, US 50 579
Lee, Jong Bum Cambridge, US 17 87
Roh, Young Hoon Cambridge, US 30 1029

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