Treatment of autism spectrum disorders with ciliary neurotrophic factor peptide mimetic

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United States of America Patent

PATENT NO 9737587
SERIAL NO

14950569

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A method of treating autism spectrum disorders using a therapeutic amount of a synthetic amino acid sequence corresponding to a portion of human ciliary neurotrophic factor (CNTF). In particular, the synthetic amino acid sequence is VGDGGLFEKKL (SEQ ID NO: 1), referred to as Peptide 6. Peptide 6 was tested and shown to exert a neuroprotective effect by modulating CNTF/JAK/STAT pathway and LIF signaling and enhancing brain derived neurotrophic factor (BDNF) expression.

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Patent OwnerAddress
THE RESEARCH FOUNDATION FOR MENTAL HYGIENE INCRIVERVIEW CENTER SUITE 301 150 BROADWAY MENANDS NY 12204

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grundke-Iqbal, Inge Staten Island, US 17 46
Iqbal, Khalid Staten Island, US 21 51

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