Functionalized liposomes useful for the delivery of bioactive compounds

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United States of America Patent

PATENT NO 9744247
SERIAL NO

14411097

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Abstract

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The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well.

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Patent Owner(s)

  • UNIVERSITAT DE BARCELONA;CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC);FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA;FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON—INSTITUT DE RECERCA;FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA);FUNDACIÓ PARC CIENTÍFIC DE BARCELONA;UNIVERSITAT AUTÒNOMA DE BARCELONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abasolo, Olaortua Ibane Barcelona, ES 2 4
Albericio, Palomera Fernando Barcelona, ES 12 27
Cabrera, Puig Ingrid Sabadell, ES 3 5
Corchero, Nieto Jose Luis Granollers, ES 3 4
Elizondo, Saez De Vicuña Elisa Barcelona, ES 1 4
Melgarejo, Diaz Marta Badalona, ES 1 4
Pulido, Martinez Daniel Viladecans, ES 2 4
Royo, Expósito Miriam Barcelona, ES 2 4
Sala, Vergés Santiago Vic, ES 3 4
Schwartz, Navarro Simón Cardedeu, ES 5 4
Veciana, Miró Jaume Barcelona, ES 7 5
Ventosa, Rull Leonor Barcelona, ES 4 5
Villaverde, Corrales Antonio Pedro El Masnou, ES 9 13

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