Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto

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United States of America Patent

PATENT NO 9745270
SERIAL NO

15144012

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Abstract

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The present invention is directed to processes and intermediates useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea (Compound I), crystalline forms and solvate forms thereof; and compositions comprising 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea, crystalline forms and solvate forms thereof prepared by processes as described herein.

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Patent Owner(s)

Patent OwnerAddress
ARENA PHARMACEUTICALS INC66 HUDSON BOULEVARD EAST NEW YORK NY 10001-2192

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carlos, Marlon Chula Vista, US 26 265
Dong, Weitong Shanghai, CN 17 67
Macias, Mark San Diego, US 12 96
Sato, Suzanne Michiko San Diego, US 11 145
Selvey, Lee Alani Poway, US 22 179

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