Catalysts and processes for the hydrogenation of amides

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United States of America Patent

PATENT NO 9745332
APP PUB NO 20140163225A1
SERIAL NO

14234344

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Abstract

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There is provided a process for the reduction of one or more amide moieties in a compound comprising contacting the compound with hydrogen gas and a transition metal catalyst in the presence or absence of a base under conditions for the reduction an amide bond. The presently described processes can be performed at low catalyst loading using relatively mild temperature and pressures, and optionally, in the presence or absence of a base or high catalyst loadings using low temperatures and pressures and high loadings of base to effect dynamic kinetic resolution of achiral amides.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA1-560 ENTERPRISE SQUARE 10230 JASPER AVENUE EDMONTON ALBERTA T5J 4P6

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bergens, Steven Alberta, CA 1 0
John, Jeremy M Alberta, CA 1 0

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