Acoustic perfusion devices

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9745548
SERIAL NO

15420073

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are disclosed for separating beads and cells from a host fluid. The method includes flowing a mixture containing the host fluid, the beads, and the cells through an acoustophoretic device having an ultrasonic transducer including a piezoelectric material driven by a drive signal to create a multi-dimensional acoustic standing wave. A drive signal is sent to drive the at least one ultrasonic transducer to create the multi-dimensional acoustic standing wave. A recirculating fluid stream having a tangential flow path is located substantially tangential to the standing wave and separated therefrom by an interface region. A portion of the cells pass through the standing wave, and the beads are held back from the standing wave in the recirculating fluid stream at the interface region. Also disclosed is an acoustophoretic device having a coolant inlet adapted to permit the ingress of a cooling fluid into the device for cooling the transducer.

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Patent Owner(s)

  • FLODESIGN SONICS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gilmanshin, Rudolf Framingham, US 34 1044
Kennedy,, III Thomas J Wilbraham, US 144 1757
Lipkens, Bart Hampden, US 124 3124
Masi, Louis Wilbraham, US 30 812
Miller, Erik Belchertown, US 82 895
Presz,, Jr Walter M Wilbraham, US 127 1759
Ross-Johnsrud, Benjamin Wilbraham, US 33 407

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