High throughput screening of populations carrying naturally occurring mutations

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United States of America Patent

PATENT NO 9745627
SERIAL NO

15434801

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Abstract

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Efficient methods are disclosed for the high throughput identification of mutations in genes in members of mutagenized populations. The methods comprise DNA isolation, pooling, amplification, creation of libraries, high throughput sequencing of libraries, preferably by sequencing-by-synthesis technologies, identification of mutations and identification of the member of the population carrying the mutation and identification of the mutation.

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  • KEYGENE N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
van, Eijk Michael Josephus Theresia Wageningen, NL 73 4322
van, Tunen Adrianus Johannes Wageningen, NL 22 865

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