Differentiation of human pluripotent stem cells

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United States of America Patent

PATENT NO 9752126
APP PUB NO 20160160182A1
SERIAL NO

14963436

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Abstract

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The present invention provides a method for increasing the expression of MAFA in cells expressing markers characteristic of the pancreatic endocrine lineage comprising the steps of culturing the cells expressing markers characteristic of the pancreatic endocrine lineage in medium comprising a sufficient amount of a cyclin-dependent kinase inhibitor to cause an increase in expression of MAFA.

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Patent Owner(s)

Patent OwnerAddress
JANSSEN BIOTECH INC800/850 RIDGEVIEW DRIVE HORSHAM PA 19044

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fryer, Benjamin Horsham, US 22 304
Rezania, Alireza Raritan, US 110 10746

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