Alkynyl-derivatized cap analogs, preparation and uses thereof

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United States of America Patent

PATENT NO 9752153
SERIAL NO

15178821

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Abstract

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Alkynyl-derivatized cap analogs, alkynyl-modified capped RNA, 1,4-disubstituted triazole-derivatized capped RNA, methods of preparation, methods of isolation, and uses thereof are provided. The “click” modification facilitates detection and isolation of capped RNAs and the 1,4-disubstituted triazole derivatives formed by the “click” reaction are useful for producing RNA transcripts and encoded protein.

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Patent Owner(s)

Patent OwnerAddress
LIFE TECHNOLOGIES CORPORATION5823 NEWTON DRIVE CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gee, Kyle Springfield, US 124 540
Kore, Anilkumar R Austin, US 8 145
Muthian, Shanmugasundaram Austin, US 7 167

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