Protein chromatography matrices with hydrophilic copolymer coatings

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United States of America Patent

PATENT NO 9758542
SERIAL NO

14355595

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Abstract

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A coating of a random copolymer of acrylamide and a second monomer, e.g. glycidoxylmethacrylate, for a silica surface is described. The coating is applied to chromatographic support structures having silica based surfaces. The coating is functionalized to produce protein chromatography matrices that are particularly useful for extracting trace amounts of biomarker molecules from biological samples.

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PURDUE RESEARCH FOUNDATION101 FOUNDRY DRIVE SUITE 2500 WEST LAFAYETTE IN 47906

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hua, Yimin Arlington, US 30 407
Wirth, Mary J West Lafayette, US 10 38
Zhang, Zhaorui West Lafayette, US 3 10

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