Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage

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United States of America Patent

PATENT NO 9758768
SERIAL NO

14666055

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This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.

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Patent Owner(s)

  • INVISTA NORTH AMERICA S A R L

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Botes, Adriana Leonora Rosedale East, GB 78 618
Conradie, Alex Van Eck Eaglescliffe, GB 78 680

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