Epidithiodioxopiperazine compound or its derivatives, and the use thereof

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United States of America Patent

PATENT NO 9765090
SERIAL NO

14286929

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Abstract

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The present invention relates to an epidithiodioxopiperazine derivative represented by the following Chemical Formula 1 or its reduced derivative; a method for preparing a compound represented by Chemical Formula 1 having improved intracellular permeability and mimicking the activity of 2-Cys-Prx in its reduced form in the cells; a pharmaceutical composition for preventing or treating vascular diseases comprising an epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient; a drug delivery device for local administration including the pharmaceutical composition; and a pharmaceutical composition for inhibiting melanoma metastasis comprising the epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient.

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Patent Owner(s)

Patent OwnerAddress
VASTHERA CO LTD504 SCIENCE BUILDING C 52 EWHAYEODAE-GIL SEODAEMUN-GU SEOUL 03760

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kang, Dong Hoon Gyeonggi-do, KR 74 517
Kang, Sang Won Seoul, KR 47 1308
Lee, Doo Jae Seoul, KR 4 1

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