Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof

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United States of America Patent

PATENT NO 9771591
SERIAL NO

15068912

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Abstract

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The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC300 THIRD STREET 3RD FLOOR CAMBRIDGE MA 02142

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bettencourt, Brian Groton, US 134 658
Fitzgerald, Kevin Brookline, US 209 2389
Frank-Kamenetsky, Maria Brookline, US 50 1080
Milstein, Stuart Arlington, US 133 755
Querbes, William Boston, US 53 413
Shulga, Morskaya Svetlana Sudbury, US 18 174

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