Crystal forms of azetidinone compounds and preparing methods thereof

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United States of America Patent

PATENT NO 9776959
APP PUB NO 20170114015A1
SERIAL NO

15386147

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Abstract

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The present invention provides crystal forms of the compound of (3R,4S)-4-(4-hydroxyphenyl)-3-[3-(4-fluorophenyl)-4-hydroxybut-2(Z)-enyl]-1-(4-fluorophenyl)-2-azetidinone (formula A). The crystal forms can be characterized by X-ray powder diffraction (XRPD) spectra, differential scanning calorimetry (DSC) spectra, infrared absorption spectra and so on. Meanwhile, the present invention also provides methods for preparing the crystal forms of the compound of formula A, pharmaceutical compositions and uses thereof.

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Patent Owner(s)

Patent OwnerAddress
ZHEJIANG HISUN PHARMACEUTICAL CO LTDJIAOJIANG DISTRICT OF TAIZHOU CITY ZHEJIANG PROVINCE 318000 ROAD OUTSIDE NO 46 TAIZHOU CITY ZHEJIANG PROVINCE 318000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bai, Hua Taizhou, CN 113 414
Liu, Chongjun Tianjin, CN 3 2
Wei, Hongyuan Tianjin, CN 3 2
Xu, Xiaojie Taizhou, CN 48 464
Zhang, Yuncai Taizhou, CN 6 9
Zhao, Xuyang Chengdu, CN 14 12

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