Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof

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United States of America Patent

PATENT NO 9776972
APP PUB NO 20160137609A1
SERIAL NO

14775232

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Abstract

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Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.

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Patent Owner(s)

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EPIZYME INC400 TECHNOLOGY SQUARE 4TH FLOOR CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boriack-Sjodin, Paula Ann Lexington, US 41 1388
Chesworth, Richard Concord, US 171 3995
Duncan, Kenneth W Westwood, US 56 1685
Jin, Lei Wellesley, US 207 2561
Mitchell, Lorna Helen Cambridge, US 69 1465
Moradei, Oscar Miguel Burlington, US 32 929
Shapiro, Gideon Gainesville, US 125 2170

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