Modular platform for multi-tissue integrated cell culture

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United States of America Patent

PATENT NO 9777252
SERIAL NO

15012577

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Abstract

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The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the organ systems are fluidically connected with a constant-volume pump.

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Patent Owner(s)

Patent OwnerAddress
THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borenstein, Jeffrey T Newton, US 102 2817
Coppeta, Jonathan Robert Windham, US 7 1151
Cuiffi, Joseph Fort Myers, US 14 177
Inman, Samuel Walker Boston, US 9 141
Mescher, Mark Joseph West Newton, US 3 31
Nguyen, Transon Van San Diego, US 2 20
Spencer, Abigail June Boston, US 5 66

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