PDE10 inhibitors and related compositions and methods

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United States of America Patent

PATENT NO 9783521
SERIAL NO

13742199

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.

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Patent Owner(s)

Patent OwnerAddress
WILMINGTON SAVINGS FUND SOCIETY FSB AS COLLATERAL AGENT500 DELAWARE AVENUE 11TH FLOOR WILMINGTON DE 19801

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cutshall, Neil S Snohomish, US 43 176
Gage, Jennifer Lynn Kenmore, US 29 144
Wheeler, Thomas Neil Raleigh, US 8 55

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