TMPRSS6 iRNA compositions and methods of use thereof

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United States of America Patent

PATENT NO 9783806
SERIAL NO

14947025

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Abstract

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The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression of TMPRSS6 and methods of treating subjects having a TMPRSS6 associated disorder, e.g., an iron overload associated disorder, such as β-thalassemia or hemochromatosis.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bettencourt, Brian Groton, US 134 658
Butler, James Lynnfield, US 112 2166
Charisse, Klaus Acton, US 73 449
Maier, Martin Belmont, US 260 4382
Rajeev, Kallanthottathil G Wayland, US 260 8660

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