PAR4 inhibitor therapy for patients with PAR4 polymorphism

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United States of America Patent

PATENT NO 9789087
SERIAL NO

15226425

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are methods for determining whether a PAR4 inhibitor should be administered to a human subject, the methods comprising administering a PAR4 inhibitor to a subject determined to have a “G” allele for a single-nucleotide polymorphism (SNP) at rs773902, and not administering a PAR4 inhibitor to a subject determined to have an “A” allele for the SNP at rs773902. A genotyping assay can be used to determine the SNP.

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Patent Owner(s)

Patent OwnerAddress
THOMAS JEFFERSON UNIVERSITY1020 WALNUT STREET PHILADELPHIA PA 19107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bray, Paul Philadelphia, US 3 4
Edelstein, Leonard Philadelphia, US 2 3
Holinstat, Michael Ann Arbor, US 14 13

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