MetAP-2 inhibitor polymersomes for therapeutic administration
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United States of America Patent
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Oct 17, 2017
Grant Date -
Dec 29, 2016
app pub date -
Sep 12, 2016
filing date -
Jun 26, 2007
priority date (Note) -
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Abstract
Described herein are MetAP-2 inhibitors and compositions and formulations thereof, and more particularly compositions and formulations of MetAP-2 inhibitors wherein the MetAP-2 inhibitor is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. The present invention also relates to compositions and formulations comprising MetAP-2 inhibitors for oral administration or administration via routes such as topical or ocular administration. The present invention also provides methods to treat conditions associated with or related to the over-expression or over-activity of MetAP-2 by administering the compositions and formulations comprising MetAP-2 inhibitors as disclosed herein.
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