Methods of producing 7-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage

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United States of America Patent

PATENT NO 9790525
SERIAL NO

14106033

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This document describes biochemical pathways for producing pimelic acid, 7-hydroxyheptanoic acid, 7-aminoheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the CoA-dependent elongation enzymes or analog enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.

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Patent Owner(s)

  • INVISTA NORTH AMERICA S.A.R.L.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Botes, Adriana Leonora Rosedale East, GB 78 618
Conradie, Alex Van Eck Eaglescliffe, GB 78 680

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