Pharmaceutical composition of killed cells with substantially retained immunogenicity

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United States of America Patent

PATENT NO 9795659
SERIAL NO

13579607

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Abstract

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This invention discloses the process for lyophilization of the treated cells which comprises the use of a solution containing Trehalose along with amphipathic polymer Polyvinylpyrrolidone. Further the invention discloses the process treating cancer cells, freezing, lyophilizing and reconstituting. Immunomodulator treated dead, but intact cancerous cells were recovered, which can subsequently be used for cancer immunotherapy.

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Patent Owner(s)

  • CADILA PHARMACEUTICALS, LTD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Desai, Nirav Manojkumar Ahmedabad, IN 6 11
Khamar, Bakulesh Mafatlal Ahmedabad, IN 34 81
Modi, Rajiv Indravadan Ahmedabad, IN 15 25
Singh, Satinder Ahmedabad, IN 15 50

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