Process for the preparation of gadobenate dimeglumine complex in a solid form
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United States of America Patent
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Oct 24, 2017
Grant Date -
Aug 11, 2016
app pub date -
Apr 15, 2016
filing date -
Nov 23, 2009
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Abstract
The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions.
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