Nanocrystalline solid dispersion compositions and process of preparation thereof

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United States of America Patent

PATENT NO 9801855
APP PUB NO 20150132385A1
SERIAL NO

14383888

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Abstract

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The present invention relates to a method of preparation of discrete particles of nanocrystalline solid dispersion, wherein said discrete particle comprises crystals of said active ingredient(s) in the matrix of the said crystallization inducer(s) and/or coexisting with crystals of crystallization inducer(s), optionally along with pharmaceutically acceptable excipient(s). An active ingredient and crystallization inducer is dissolved in a solvent or solvent mixture and then dried to obtain discrete particles of 0.5 to 20 micron size. Each particle consists of crystals of active ingredient in the range of 10-1000 nm dispersed in the matrix of crystallization inducer.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH (NIPER)SECTOR-67 S A S NAGAR MOHALI PUNJAB 160062

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bansal, Arvind Kumar Punjab, IN 1 2
Bapurao, Pawar Yogesh Punjab, IN 1 2
Bhaskarao, Shete Ganesh Punjab, IN 1 2
Dantuluri, Ajay Kumar Raju Punjab, IN 1 2

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