Synthetic polyurethane composite

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United States of America Patent

PATENT NO 9801946
SERIAL NO

13868077

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Abstract

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Embodiments of the present inventions comprise composites of polyurethane(s), osteoconductive matrix, and, optionally, a growth factor. Embodiments further comprise methods of making such composite and uses thereof. The osteoconductive matrix can be a tricalcium phosphate, bioglass, or the like, and can include particles that are surface modified. Growth factors can be provided in powder form, including bone morphogenic proteins such as rhBMP-2. A composition may be moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells.

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Patent Owner(s)

  • VANDERBILT UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dumas, Jerald Nashville, US 2 32
Guelcher, Scott A Thompson Station, US 28 386
Harmata, Andrew Nashville, US 1 30
Prieto, Edna M Nashville, US 2 43
Talley, Anne Nashville, US 1 30
Zienkiewicz, Katarzyna Nashville, US 3 48

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