Adenovirus derived helper virus for enhancing recombinant parvovirus production

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United States of America Patent

PATENT NO 9803219
SERIAL NO

13627554

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Described is an adenovirus derived helper virus which may comprise the adenoviral DNA sequences for E2a, S4 (orf6), the VA1 RNA gene, and the parvovirus VP capsid gene unit. Also described is a method of efficiently preparing a recombinant parvovirus (particle) which is based on the use of various adenoviral derived helper viruses/vectors.

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DEUTSCHES KREBSFORSCHUNGSZENTRUMIM NEUENHEIMER FELD 280 HEIDELBERG 69120

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
El-Andaloussi, Nazim Heidelberg, DE 5 8
Endele, Max Wilhelmsfeld, DE 1 0
Leuchs, Barbara Heidelberg, DE 19 15
Marchini, Antonio Heidelberg, DE 15 9
Rommelaere, Jean Heidelberg, DE 48 78

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