Microarray-based assay integrated with particles for analyzing molecular interactions

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United States of America Patent

PATENT NO 9803236
SERIAL NO

13814213

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A microarray-based assay is provided, which is used for analyzing molecular interactions, including polynucleotides, polypeptides, antibodies, small molecule compounds, peptides and carbohydrates. Such method comprises coupling a target molecule to a particle and then binding to a probe molecule on microarray. In particular, multiplexed genetic analysis of nucleic acid fragments can be implemented. Specific genes, single nucleotide polymorphisms or gene mutations, such as deletions, insertions, and indels, can be identified. Coupled with microarray, the particles, themselves or further modified, facilitate the detection of results with non-expensive devices or even naked eyes. This technology enables the detection and interpretation of molecular interactions in an efficient and cost effective way.

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Patent Owner(s)

Patent OwnerAddress
TSINGHUA UNIVERSITY100084 HAIDIAN DISTRICT TSINGHUA YUAN BEIJING NO 1 MUNICIPAL DISTRICT BEIJING CITY 100084
CAPITALBIO TECHNOLOGY CORPORATION88 KECHUANG 6TH STREET BUILDING C YIZHUANG BIOMEDICAL PARK BDA BEIJING 101111

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Jing Beijing, CN 135 2071
Xiang, Guangxin Beijing, CN 9 14
Xing, Wanli Beijing, CN 36 63
Zhang, Guanbin Beijing, CN 10 9

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