Chromatography apparatus and methods using multiple microfluidic substrates
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United States of America Patent
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Oct 31, 2017
Grant Date -
May 7, 2015
app pub date -
Jan 12, 2015
filing date -
May 29, 2009
priority date (Note) -
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Abstract
An apparatus for chemical separations includes a first substantially rigid microfluidic substrate defining a first fluidic port; a second substantially rigid microfluidic substrate defining a second fluidic port; and a coupler disposed between the first and second substrates, the coupler defining a fluidic path in fluidic alignment with the ports of the first and second substrates. The coupler includes a material that is deformable relative to a material of the first substrate and a material of the second substrate. The substrates are clamped together to compress the coupler between the substrates and form a fluid-tight seal.
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