Methods of reducing basophil levels

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United States of America Patent

PATENT NO 9815895
APP PUB NO 20140004109A1
SERIAL NO

13934271

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.

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Patent Owner(s)

  • ASTRAZENECA AB;BIOWA;BIOWA, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koike, Masamichi West Windsor, US 34 427
Spitalny, George L Yardley, US 6 88
Wheeler, Alistair Northborough, US 3 49
White, Barbara Finksburg, US 9 52

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