Inhibitors of ERCC1-XPF and methods of using the same

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United States of America Patent

PATENT NO 9821008
APP PUB NO 20160296556A1
SERIAL NO

15038585

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Abstract

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Compositions and methods for inhibiting the DNA repair protein complex, ERCC1-XPF, and methods to enhance clinical responses to anticancer drugs that interact with DNA such as cisplatin, and to overcome drug resistance due to DNA repair mechanisms, are described.

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Patent Owner(s)

  • THE UNIVERSITY OF TOLEDO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erhardt, Paul W Toledo, US 46 194
Patrick, Stephan M Toledo, US 1 0
Trabbic, Christopher Toledo, US 3 5

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