Anti-IL-6 antibody for use in the treatment of cachexia

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United States of America Patent

PATENT NO 9821057
SERIAL NO

14672543

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is directed to therapeutic methods and compositions, especially subcutaneous and intravenous composition using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments, the anti-IL-6 antibodies will be humanized and/or will be aglycosylated. Also, in preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level. In another preferred embodiment, the patient's survivability or quality of life will preferably be improved.

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Patent Owner(s)

  • ALDERBIO HOLDINGS LLC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Latham, John A Seattle, US 92 1177
Litton, Mark Seattle, US 24 582
Schatzman, Randall Redmond, US 18 517
Smith, Jeffrey T L Bellevue, US 93 1198

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