Asymmetric synthesis of a substituted pyrrolidine-2-carboxamide

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United States of America Patent

PATENT NO 9828340
SERIAL NO

14766049

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The invention relates to a process for the preparation of 4-{[(2R,3S,4R,5S)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid of the formula (I)

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HOFFMANN-LA ROCHE INCGREAT NOTCH 150 CLOVE ROAD 8TH FLOOR LITTLE FALLS NJ 07424

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fishlock, Daniel Basel, CH 4 77
Gu, Chen Lake Hiawatha, US 14 34
Rege, Pankaj Devdatta Basel, CH 1 0
Sarma, Keshab Sunnyvale, US 28 765
Shu, Lianhe Livingston, US 10 25

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