Class of near infrared optical probes for biological applications

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United States of America Patent

PATENT NO 9845318
SERIAL NO

14612890

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Abstract

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2,5-Bis(benzoxazol-2′-yl)benzene-1,4-diol derivatives (Zinhbo derivatives) are used to detect zinc ions and have particular application in vivo and in vitro. Zinhbo derivatives upon excitation give a florescence response emission that can be used to determine the presence of zinc cation in solution. Zinhbo derivatives complexed with zinc cations upon excitation can produce a florescence response emission in the visible and near infrared range. Zinhbo derivatives complexed with zinc cations exhibit a large stoke shift between the excitation and emission wavelengths.

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Patent OwnerAddress
THE UNIVERSITY OF AKRON302 E BUCHTEL COMMON AKRON OH 44325

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pang, Yi Copley, US 33 116
Xu, Yongqian Yangling, CN 4 6

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