Enzymatic methods for genotyping on arrays

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United States of America Patent

PATENT NO 9845494
APP PUB NO 20080131894A1
SERIAL NO

11874848

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Abstract

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The invention relates to methods for enzymatic, genotyping of polymorphisms on solid supports. In some aspects the methods include ligation of allele or base specific interrogation probes to an array probe. The array probe is labeled by ligation of the interrogation probe. Ligation is dependent on the identity of the base immediately adjacent to the end of the array probe. In other aspects array bound probes are labeled by template dependent extension.

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Patent Owner(s)

Patent OwnerAddress
AFFYMETRIX INC5823 NEWTON DRIVE CARLSBAD CA 92008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fu, Glenn K Dublin, US 56 4444
Jones, Keith W Sunnyvale, US 45 1499

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