Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9850463
SERIAL NO

13756489

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The production of high quality retinal pigmented epithelium (RPE) cells is necessary for research and potential therapeutic uses. Especially desirable are methods for the production of RPE cells using xeno-free culture conditions. Disclosed herein are novel methods for the production of RPE cells from pluripotent cells with high yields, including xeno-free production methods. Also provided are methods of efficiently isolating RPE cells from cultures containing heterogeneous cell types, allowing for substantially pure RPE cell cultures to be established. Additionally, novel methods for the cryopreservation of RPE cells are provided.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF SOUTHERN CALIFORNIA3720 SOUTH FLOWER STREET FLOOR 3 - MC 0705 LOS ANGELES CA 90089

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clegg, Dennis Ventura, US 5 111
Conti, Lisa Goleta, US 2 40
Hikita, Sherry Santa Barbara, US 4 42
Hinton, David Venice Beach, US 12 146
Hu, Qirui Santa Barbara, US 2 40
Johnson, Lincoln Santa Barbara, US 2 40
Maloney, Michelle Santa Barbara, US 2 40
Miller, Liane San Francisco, US 4 49
Presbrey, Chelsea Flagstaff, US 2 40
Tsie, Marlene Santa Barbara, US 2 40

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Jun 26, 2025
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jun 26, 2029
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00