Ultra-high-sensitive assay of protein and nucleic acid and kit, and novel enzyme substrate

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United States of America Patent

PATENT NO 9851309
SERIAL NO

14006317

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Abstract

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Provided is a ultra-high-sensitivity assay in which the assay can be made on a commonly used assay apparatus such as an absorptiometer and a plate reader or with naked eyes. The high-sensitivity assay in which the assay can be made on a commonly used assay apparatus or with naked eyes can be provided by combining an enzyme cycling method using thio-NAD(P) as a coenzyme, a labeling enzyme and a substrate for the labeling enzyme optimally, and by amplifying thio-NAD(P)H, which is a signaling substance, exponentially and then quantifying the thio-NAD(P)H colorimetrically.

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Patent Owner(s)

Patent OwnerAddress
BIOPHENOMA INC22-3 NISHIWASEDA 1-CHOME SHINJUKU-KU TOKYO 1690051

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ito, Etsuro Hokkaido, JP 7 66

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